Sulfadoxine

Combination Sulfadioxine and Pyrimethamine (Sulphadar) Tablets

Sulfadoxine (Sulphadoxine) is an antibiotic in the Sulfonamide family. It is primarily used in combination with Pyrimethamine for the treatment of malaria.

Sulfadoxine is rarely used as a treatment for acne. There is minimal clinical research or laboratory testing on the utility of Sulfadoxine as an acne treatment. Laboratory testing indicates that the acne-causing P. acnes bacterium is tends to be moderately sensitive to Sulfonamide family antibiotics, such as Sulfadoxine.

For the treatment of active acne symptoms, other Sulfonamide family antibiotics (eg. Sulfamethoxazole, Dapsone. Sulfadiazine) are more commonly prescribed.

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Sulfadimethoxine

Sulfadimethoxine (Albon) 250mg Tablets

Sulfadimethoxine (Albon) is an antibiotic in the Sulfonamide family. It is primarily used in veterinary medicine, but it is approved for human use in several countries (eg. Russia).

Sulfadimethoxine is rarely used as an acne treatment. For the treatment of active acne symptoms, other oral Sulfonamide antibiotics (eg. Sulfamethoxazole) are far more commonly prescribed. Sulfadimethoxazole is primarily available in oral formulations.

Clinical research on this medication as an acne treatment is limited,. But the research that does exist indicates that Sulfadimethoxine is a partially effective treatment for patients with moderate to severe acne vulgaris. However, this research also found that Tetracycline and Erythromycin were substantially more effective than Sulfadimethoxine.

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Spiramycin

Spiramycin Tablets

Spiramycin (Spirex) is an antibiotic in the Macrolide family. It has both antibacterial and antiparasitic properties. Spiramycin is used to treat a limited range of infections, and this medication is not available in all countries.

Spiramycin is rarely used as a treatment for acne. There is minimal clinical research into the efficacy of Spiramycin as an acne treatment. Other members of the Macrolide family (eg. Erythromycin, Azithromycin, etc) are more widely available and commonly used. Laboratory testing indicates that the acne-causing P. acnes bacteria is less susceptible to Spiramycin than to other Macrolide family antibiotics.

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Sparfloxacin

Sparfloxacin (Zospar) 100mg Tablets

Sparfloxacin (Zospar) is an antibiotic in the Quinolone family. It is used to treat certain types of bacterial infections of the respiratory tract, urinary tract and skin.

Sparfloxacin is rarely used as a treatment for acne. There is minimal clinical research into the efficacy of Sparfloxacin as a treatment for active acne symptoms. However, laboratory testing does suggest that Sparfloxacin has certain properties that could make it a uniquely effective acne treatment.

Antibiotic susceptibility testing indicates that the acne-causing P. acnes bacterium is highly sensitive to Sparfloxacin. In addition, Sparfloxacin is absorbed by certain types of white blood cells, which may help the immune system better control the growth of acne-causing bacteria. Lastly, Sparfloxacin has been shown to accumulate in the skin following oral administration.

More research is needed on the utility of Sparfloxacin for the treatment of acne, but it is an antibiotic that deserves further investigation.

Sparfloxacin is only available in oral formulations and this medication is not available in all countries (eg. United States).

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Roxithromycin

Roxithromycin (Cyrox) Tablets

Roxithromycin (Roxicin) is an antibiotic in the Macrolide family. It is used to treat certain types of respiratory, urinary and soft tissue infections that are caused by susceptible bacteria.

Roxithromycin is occasionally used to treat acne. Clinical research has indicated that Roxithromycin (and other Macrolide family antibiotics) can be effective acne treatments. Roxithromycin may be particularly helpful for the treatment of acne because this antibiotic can accumulate inside of certain types of white blood cells. This accumulation may help the immune system better control the growth of the acne-causing P. acnes bacterium. This accumulation may also help limit the inflammation that causes acne symptoms such as pimples, nodules, cysts and scars.

Laboratory testing has demonstrated that Macrolide family antibiotics, including Roxithromycin, are active against P. acnes bacteria. However, P. acnes bacteria that are highly resistant to Macrolide family antibiotics are becoming increasingly common in many places in the world. Patients with acne infections caused by these resistant bacteria are less likely to see a benefit from antibiotic therapy with Roxithromycin, and other Macrolides.

Roxithromycin is not available in all countries (eg. United States).

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Rifapentine

Rifapentine (Priftin)

Rifapentine (Priftin) is an antibiotic in the Rifamycin family. It is an important component of the combination antibiotic therapy used to treat tuberculosis, and other mycobacterial infections.

Rifapentine is not generally used in the treatment of acne. Laboratory testing indicates that the acne-causing Propionibacterium acnes bacterium is highly sensitive to Rifamycin family antibiotics, including Rifapentine.

Rifapentine and other Rifamycin family antibiotics may be useful components of comprehensive treatment regimens for people with severe acne symptoms. Additional clinical research and patient reports are needed to evaluate the utility of this family of antibiotics for the treatment of acne.

Rifapentine is not yet available in generic formulations, therefore the cost of this medication can be quite high in many countries.

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Rifampicin

Rifampicina 300mg Capsules

Rifampicin (Rifampin) is an antibiotic in the Rifamycin family. It is an important component of the combination antibiotic therapy used to treat tuberculosis. Rifampicin is used to treat several types of infections, particularly those that are caused by anaerobic gram-positive bacteria, which is a group of bacteria that includes the acne-causing Propionibacterium acnes bacterium.

Rifampicin is occasionally used to treat certain types of severe acne. Laboratory testing indicates that P. acnes bacteria are very sensitive to Rifamycin family antibiotics, including Rifampicin. There is also some clinical research that suggests Rifampicin can be helpful for patients with moderate to severe acne symptoms.

Rifampicin and other Rifamycin family antibiotics may be useful components of comprehensive treatment regimens for people with severe acne symptoms. Additional clinical research and patient reports are needed to evaluate the utility of this family of antibiotics for the treatment of acne.

Rifampicin can inhibit the activity of hormonal birth control. Sexually active women of child-bearing age should take additional precautions to prevent pregnancy while taking this medication. Rifampicin is very inexpensive in many parts of the world, but the monthly cost can be quite high in certain countries (eg. United States).

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Rifabutin

Rifabutin (Mycobutin) Capsules

Rifabutin (Mycobutin) is an antibiotic in the Rifamycin family. It is primarily used in the treatment of mycobacterial infections (eg. tuberculosis).

Rifabutin is rarely used for the treatment of acne and their is very little clinical research into the efficacy of Rifabutin as an acne treatment.

Rifabutin is active against many gram-positive bacteria, including the acne-causing Propionibacterium acnes. Laboratory testing indicates that P. acnes bacteria are very sensitive to Rifamycin family antibiotics, including Rifabutin.

Rifamycin family antibiotics may be useful components of acne treatment regimens, particularly for individuals with moderate to severe acne symptoms. But more clinical research and patient reports are needed to evaluate the utility of this family of antibiotics for the treatment of acne.

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Pristinamycin

Pristinamycin (Pyostacine) 500mg Tablets and Packaging

Pristinamycin (Pyostacine) is an antibiotic that is used to treat certain types of infections caused by gram-positive bacteria (eg. Staph infections). Pristinamycin is a natural combination of two complementary antibiotics – Pristinamycin IA an Pristinamycin IIA. Pristinamycin IA is a cyclic hexadepsipeptide antibiotic, and Pristinamycin IIA is in the Macrolide family of antibiotics.

Pristinamycin is rarely used as an acne treatment, but laboratory testing indicates that the acne-causing P. acnes bacterium is susceptible to Pristinamycin. Pristinamycin is occasionally used to treat non-acne infections that are caused by P. acnes bacteria.

Pristinamycin is only available in a few countries. But in countries where it is available, Pristinamycin is an antibiotic that warrants further investigation as an acne treatment.

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Penicillin V

Penicillin V Potassium 500mg Tablets

Penicillin V (Phenoxymethylpenicillin) is an antibiotic in the Penicillin family. Penicillin V is used to treat many different types of bacterial infections. This antibiotic is primarily active against gram-positive bacteria, which includes the acne-causing Propionibacterium acnes bacterium.

Penicillin V is available in topical and oral formulations. Penicillin V is occasionally used as an oral antibiotic for the treatment of acne. For topical use, the closely-related Penicillin G is more commonly prescribed.

Penicillin V and Penicillin G are notable because they consistently score very well in laboratory testing of antibiotic susceptibility of the P. acnes bacterium. These antibiotics kill P. acnes bacteria at very low concentrations, and Penicillin-resistant P. acnes bacteria are very uncommon.

Clinical research and patient reports have indicated that oral treatment with Penicillin family antibiotics (eg. Amoxicillin, Ampicillin, Penicillin V) is effective at improving acne symptoms for many patients. The topical use of Penicillin also appears to be a useful acne treatment.

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