Corticosteroid Injections are administered by dermatologists directly into an acne nodule or cyst to relieve the inflammation. The inflammatory immune response in an acne lesion can cause significant damage to the surface of the skin, and the supportive tissue underneath. Corticosteroid injections are used to treat large inflammatory acne lesions that can permanently damage the skin and lead to the formation of acne scars.
Injections of anti-inflammatory corticosteroids can inhibit the recruitment and activation of immune cells, stopping the inflammatory process. However, the effect of corticosteroid injections is temporary. Because corticosteroids inhibit normal immune system function, frequent or systemic use of corticosteroids may occassionally worsen acne symptoms by allowing the bacteria that trigger acne lesions to proliferate. The injectable corticosteroid most commonly used in acne treatment is Triamcinolone.