Levofloxacin (Levoflox) is an antibiotic in the Quinolone family. It is used to treat a range of bacterial infections, including respiratory, eye and urinary tract infections.

Levofloxacin is rarely used as an acne treatment. However, laboratory testing indicates that the acne-causing P. acnes bacterium is generally susceptible to this antibiotic. Several studies have indicated that oral Levofloxacin may be more effective at controlling acne symptoms than other members of the Quinolone antibiotic family (eg. Ciprofloxacin).

Levofloxacin is available in oral and topical formulations. Oral Levofloxacin is a more commonly used as an acne treatment than topical Levofloxacin. Topical Levofloxacin is generally available as an opthalmic ointment, but these medications can be applied directly to the skin.

Levofloxacin (and other Quinolones) are not recommended for use in pregnant women and growing children because these medications can cause musculoskeletal side effects in people with growing bones and teeth. Quinolones also tend to have moderately higher rates of adverse events than many other forms of oral antibiotics.

The cost of Levofloxacin is low in many countries, but it can be very expensive in certain places where the supply is more tightly controlled (eg. United States).

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