Tetracycline is a broad spectrum antibiotic in the Tetracycline family. It is used to treat many different kinds of bacterial infections, including those of the respiratory tract, urinary tract and skin.

Tetracycline was once a popular acne treatment, but it has largely been replaced by two closely related antibiotics – Doxycycline and Minocycline. Tetracycline is available in oral and topical formulations, both of which are used as acne treatments.

Tetracycline can be an effective acne treatment, but tetracycline-resistant P. acnes bacteria are becoming common in many regions of the world. Some acne patients find that Tetracycline significantly improves their acne symptoms. But many other patients (particularly those from the United States and Europe) find that antibiotics in the Tetracycline family are ineffective treatments for controlling their acne symptoms.